Antiproliferative Activity of PEG-PEI-SWCNTs against AMJ13 Breast Cancer Cells

Single-walled carbon nanotubes (SWCNTs) involving polyethylene glycol (PEG) and polyethyleneimine (PEI), which contain amines, were produced analyzed using X-ray diffraction (XRD), UV–vis spectroscopy, Raman spectroscopy (RS), transmission electron microscopy (TEM) for the spectral structural analyses of PEG-PEI-SWCNTs. PEG-PEI-SWCNTs demonstrated peaks at 300.98 nm, have a broad peak 2θ = 23.51, linked to 002 with d-spacing (3.7816), crystalline sizes 8.48 nm. In PEG-PEI-SWCNTs, TEM images accumulation SWCNTs PEG-PEI due an increased main grain size functionalization 80.68 The D G bands in moved 1,292 1,586 cm−1, respectively. are observed as bundle inhomogeneous, long-curved accumulates containing multitudes tubes. tubular structure that demonstrates particles scattered alongside nanotube sidewalls, indicate PEG PEI conjugated SWCNTs. Cytotoxicity evaluation (6.25–100 µg/mL) breast cancer AMJ13 cell line was conducted 24 72 hr, results showed enhanced toxicity tumor cells decreased cytotoxicity against rhabdomyosarcoma (RD) normal cells.